Although schistosomiasis is not often fatal, it is so debilitating that it has become an economic drain on many developing countries.
it is so debilitating that it has become an economic
it is of such debilitation, it has become an economical
so debilitating is it as to become an economic
such is its debilitation, it becomes an economical
there is so much debilitation that it has become an economical
economic not economical,排除BDE,在AC中选择
(C)选项中become体现的是action,而不是static state.
you don't use so ADJ as to VERB unless the VERBdescribes some sort of state/condition.
A选项中两个it都指代schistosomiasis (血吸虫病)
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