In human hearing, subtle differences in how the two ears hear a given sound help the listener determine the qualities of that sound.
in how the two ears hear a given sound help the listener determine
in the two ears hearing a given sound help the listener in determining
in how a sound is heard by the two ears helps the listener determine
between how the two ears hear a given sound helps the listener in determining
between how a sound is heard by the two ears help the listener in determining
The in vs. between issue is an idiom. I say differences in X (just one thing) or differences between X and Y (two things). This sentence has one thing: how the two ears hear a given sound. So, I need "differences in." Elim D and E.
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