The investigations of many psychologists and anthropologists support the generalization of there being little that is a significant difference in the underlying mental processes manifested by people from different cultures.
of there being little that is a significant difference
of there being little that is significantly different
of little that is significantly different
that there is little that is significantly different
that there is little of significant differences
e.g., my grandmother doesn't like the idea of combat sports.
in the case of generalization, though, you can't follow it with "of" + noun, because generalizations aren't represented by nouns -- they are represented by statements (clauses). you can introduce a clause with "that", but not with "of".
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