The investigations of many psychologists and anthropologists support the generalization of there being little that is a significant difference in the underlying mental processes manifested by people from different cultures.
of there being little that is a significant difference
of there being little that is significantly different
of little that is significantly different
that there is little that is significantly different
that there is little of significant differences
the most objective error in choice (e) is its use of "little" for a quantity of differences.
differences (like virtually all plural nouns) are countable, so you can't use "little" to describe them. if this choice said few significant differences, it would be legitimate.
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