The Nobel Prize in chemistry was awarded to three scientists for their discovery that plastic can be made electrically conductive--an advance that has led to improvements in film, television screens, and windows.
that plastic can be made electrically conductive--an advance that has led
that plastic can be made electrically conductive--this advance leading
that plastic can be made to be electrically conductive, and this advance led
of plastic's ability to be made electrically conductive, with this advance leading
of plastic being able to be made electrically conductive--an advance that has led
C:you can't start with 'this advance' unless you're writing a new independent clause (as you would if you were following a coordinating conjunction such as 'and', 'but', etc.) if you're going to use a modifier like this, it should start with 'AN advance' (as does choice A).
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