Ozone, a special form of oxygen that screens out harmful ultraviolet rays, reaches high concentrations twelve miles above Earth, where it has long appeared that it was immune from human influence; we have now realized, though, that emissions of industrial chlorofluorocarbons deplete the ozone layer.
has long appeared that it was immune from
has long appeared to have been immune from
has long appeared as being immune to
had long appeared immune to
had long appeared that it was immune to
E: 无论第一个it 是形式主语还是代表ozone都不对 - appear 是系动词后加表语,所以不用再加it
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