In virtually all types of tissue in every animal species, dioxin induces the production of enzymes that are the organism's trying to metabolize, or render harmless, the chemical that is irritating it.
trying to metabolize, or render harmless, the chemical that is irritating it
trying that it metabolize, or render harmless, the chemical irritant
attempt to try to metabolize, or render harmless, such a chemical irritant
attempt to try and metabolize, or render harmless, the chemical irritating it
attempt to metabolize, or render harmless, the chemical irritant
The -ing form of a verb can be used as a noun (e.g., running is her favorite sport), but it is often awkward, particularly when used with a possessive, as in this case. Substituting the noun attempt for the gerund trying eliminates the problem. While chemical that is irritating it and chemical irritating it are both grammatically correct and could be appropriate in some usages, they are excessively wordy for this context.
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